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Zebra ZD421 4-inch Label Printers

The ZD421 4-inch desktop label printer delivers the features, flexibility, reliability, and security you need. Built on the legacy of the GK420 and ZD420, the ZD421 offers a new and more intuitive user interface for simpler operation, a range of connectivity options, and more printing power to run more tasks, perform more operations simultaneously and maintain security. Available in Thermal Direct and Thermal Transfer models with 203 dpi and 300 dpi resolution. 


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  • Prints 1D and 2D barcodes
  • Easy to operate with an intuitive user interface
  • Field installable dispenser — label peel and present with label present sensor; field installable cutter

  • Field installable Wi-Fi

  • See status immediately with the five LED icons
  • Designed to handle advancing technology
  • Backward compatible with virtually any existing printer
  • Turn your ZD421 into a portable printer using the battery option
  • Movable media sensor lets you use almost any media for greater flexibility across a variety of use cases
  • Print DNA suite of software gets your printer up and running quickly and gives you the ability to easily manage and troubleshoot your networked printers from one remote location
  • PrintSecure, part of Print DNA, offers unparalleled security and shields you from cyberattacks
  • 2-year standard warranty

Visit our Shop to learn more or browse our range of desktop label printers.

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